Synthesis of 14C-Labelled Benzofuran Derivative

Metabolism of 14C-labelled alphaxalone in man.

The metabolism of 14C-labelled alphaxalone, dispensed as Althesin, was studied in normal patients, patients with obstructive jaundice and patients with chronic renal disease and anuria. The radioactive label was removed rapidly from the plasma following i.v. administration. The major portion of the label was excreted in the urine. In patients with normal renal function 14C-labelled alphaxalone ...

Metabolism of 14C-ring-labelled paracetamol in humans.

Liquid-Scintillation Counting of 14C-Labelled Animal Tissues

Developments of liquid-scintillation counting as a practical method for the assay of radioisotopes in biological samples followed work by Reynolds, Harrison & Salvini (1950) and Kailmann & Furst (1950). Reviews of progress and developments in liquid-scintillation counting have been given by Davidson & Fiegelson (1957) and Bell & Hayes (1958). Guinn (1958) and Stitch (1959) have reviewed the adv...

Utilization of 14C-labelled Escherichia coli by rats.

1. Escherichia coli was grown on 14C-labelled glucose and fractions representing "whole cells", "cell contents" and "cell walls" were administered orally to rats. 2. 14C appearing as 14CO2 in the expired air and as unidentified radioactive products in urine and faeces was measured until the cumulative recovery showed little change with time. 3. All fractions were digested. The digestibility of ...

The metabolism of 14c-labelled bicarbonate in the cat.